Processed DiGSeE scores of relevance to schizophrenia of each gene set signature

Summarised schizophrenia relevance score of each gene set from the genewise scores downloaded from DiGSeE database. Scores were log-transformed. Details on the processing of raw scores are available in the Supplementary Methods in the reference.

data("digsee", package = "brainClass")

Format

A list object.

digsee

A list object of data frames with summarised DiGSeE schizophrenia relevance scores for different gene set collections. Each data frame contains three columns. `prop` means the proportion of genes with an effective DiGSeE score. `sumScore` is the sum of all scores; and `avgScore` stores the mean score of each gene set.

References

Kim, J., So, S., Lee, H. J., Park, J. C., Kim, J. J., & Lee, H. (2013). DigSee: disease gene search engine with evidence sentences (version cancer). Nucleic acids research, 41(W1), W510-W517.

Li, M., Kessler, D., Arroyo, J., Freytag, S., Bahlo, M., Levina, E., & Yang, J. Y. H. (2020). Guiding and interpreting brain network classification with transcriptional data. bioRxiv.

Examples

data("digsee", package = "brainClass")